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Prof. Stephan Hann

University of Natural Resources and Life Sciences (BOKU), Institute of Analytical Chemistry,  Austria

DC 10 co-supervisor

Stephan Hann is Full Professor and Head of the Institute of Analytical Chemistry at BOKU University in Vienna (Austria). His research encompasses the development and application of analytical methods in mass spectrometry–based metabolomics and ultra-trace analysis applied to a broad range of research topics including biotechnology, environmental and food sciences. A strong focus in his research is placed on metrology including robust estimations of the uncertainty of measurement for IM-derived ion collision cross sections (CCS) and making this parameter accessible in regulated methods.

“IM-HRMS is a powerful analytical technology as it can be a generic approach that provides separation and yields CCS and accurate mass data for all ions in complex samples. MobiliTraIN is exciting as the new fundamentals and standards we develop can help us bring IM-HRMS into the regulatory sector where all these benefits can be finally applied.”

Selected Publications

  1. Mairinger, T., Causon, T.J., Hann, S. 2018. The potential of ion mobility mass spectrometry for non-targeted metabolomics. Curr. Opin. Chem. Bio. 42, 9-15 https://doi.org/10.1016/j.cbpa.2017.10.015 
  2. Mairinger, T., Kurulugama, R., Causon, T., Stafford, G., Fjeldsted, J., Hann, S. 2019. Rapid screening methods for yeast sub-metabolome analysis on a high-resolution IM-Q-TOF mass spectrometer. Rapid Commun. Mass Spectrom. 33, 66-74 https://doi.org/10.1002/rcm.8420
  3. Causon, T., Hann, S. 2020. Uncertainty estimations for collision cross section determination via uniform field drift tube-ion mobility-mass spectrometry. J. Am. Soc. Mass Spectrom.  31, 2102-2110 https://pubs.acs.org/doi/10.1021/jasms.0c00233
  4. Stow, S.M., Causon, T.J., Zheng, X., Kurulugama, R.T., Mairinger, T., May, J.C., Rennie, E., Baker, E.S., Smith, R.D., McLean, J.A., Hann, S., Fjeldsted, J.C. 2017. An interlaboratory evaluation of drift tube ion mobility collision cross section measurements. Anal. Chem. 89, 9049-9055 https://doi.org/10.1021/acs.analchem.7b01729